Short-term exposure to pregnancy levels of estrogen prevents mammary carcinogenesis

Short-term exposure to pregnancy levels of estrogen prevents mammary carcinogenesis.

It is well established that pregnancy early in life reduces the risk of breast cancer in women and that this effect is universal. This phenomenon of parity protection against mammary cancer is also observed in rodents. Earlier studies have demonstrated that short-term administration of estradiol (E) in combination with progesterone mimics the protective effect of parity in rats. In this study, ...

Short Communication: Haematological and immunological responses of sea bass (Dicentrarchus labrax) to a short-term exposure to increased water levels of nitrate

Short Communication: Haematological and immunological responses of sea bass (Dicentrarchus labrax) to a short-term exposure to increased water levels of nitrate

Short-term exposure to high levels of natural external gamma radiation does not induce survival adaptive response

Background: In some areas of Ramsar, a city in northern Iran, residents receive a much higher annual radiation exposure than is permitted for radiation workers. Induction of adaptive response in residents of Ramsar has been reported previously. In this study induction of such a response in short term exposure to high background levels of gamma radiation is investigated. Materials and M...

Inhibition of rat mammary carcinogenesis by short dietary exposure to retinyl acetate.

tion has been achieved by beginning the retinoid supplement 7 days after a single dose of DMBA; at this time, the binding of the carcinogen to mammary panenchymalcell DNA and protein is complete, and unreacted DMBA is no longer detectable in the gland (8, 12). Comparatively little is known about possible inhibitory effects of retinoids on the early stage of mammary cancinogenesis and whether an...